Fats and oils are categorized in a variety of ways, as saturated, unsaturated, cholesteric, steroidal, blah, blah. In truth, all are important and all can be synthesized in the body for normal functioning…except for two. These are linoleic acid and alpha-linolenic acid. These two form the building blocks for thousands of functions that are essential for body functioning, such as controlling inflammation (a chronic problem among many) controlling blood pressure, building hormones and maintaining cell wall fluidity. The human body is a marvelously self-repairing and self-protecting organism, provided all the essential nutrients are present. These are two of them. Some info…
But FIRST! If you have a limited
budget, time or space to read, make this book one of your choices to buy. It is
a comprehensive and outstanding book by one of the most knowledgeable people in
the field, Udo Erasmus. Title: Fats that Heal Fats that Kill publ. Alive
Books.
Now:
Here are the structures of four biggies in the fat usage
for the body.
Linoleic Acid (LA)
alpha-Linolenic
Acid (ALA)
Docosohexanoic Acid (DHA)
Eicosapentanoic Acid (EPA)
First, the last two, DHA and EPA can be synthesized in
the body from specifically from the second, ALA. These are POWERFUL in the body
and are the reason why fresh cold water fish has been so highly promoted
lately. DHA and EPA are the two functional oils obtained from fish like tuna,
salmon and mackeral. So, if we can make them, why eat them? Later, more needs
to be told in this story, yet. It is very important to note a couple of things
before moving on. 1.) Notice the double lines in each of the chemical
structures. These are what make these “polyunsaturated” If there were only 1
double line, it would be monounsaturated and all single lines are saturated.
2.) Notice that the double lines are all on the same side. Although there is a
lot of chemistry to explain this, the bottom line is that this fact allows the
molecules to twist around a certain way. If the double lines are on different
sides, then these are called “trans-fatty acids” or “trans fats”. These,
FINALLY are hitting the mainstream media for the incredibly toxic role they
play in the body. More is discussed later, but more comprehensive discussion is
in the section on Modern Foods. First, some fast fat facts.

This chart shows the biochemical pathways associated with
these LA and ALA. Notice the right side
pathway. Near the bottom are the EPA and DHA fats. These two fats have the
properties that they prevent excessive blood clotting and thickening, lower
blood triglycerides and blood pressure, fight cancer and more. Also, EPA is
converted into series 3 prostaglandins. More about these in a minute. The left
hand side pathway leads to Series 1 and Series 2 prostaglandins. Also, they
lead to Arachidonic Acid. Now, a word
about how these play biochemical roles.
Metabolic functions that involve essential fats are:
Energy Production
Oxygen Transfer
Hemoglobin Production
Membrane components of cells and cellular
organelles. This is EXTREMELY important for proper functioning of all cells in
the body. The cells don’t work, you don’t work.
Cell Division
Brain Function
Prostaglandins
I’ve highlighted the last item because of the tremendously wide variety and balance these play in the body. In short, prostaglandins are roughly divided into three series. Functions include:
|
Series 1 and 3 |
Series 2 |
|
Prevents blood clotting |
Promotes blood clotting |
|
Reduces pain and inflammation |
Promotes pain and inflammation |
|
Helps remove sodium from blood |
Helps retain sodium in blood |
|
Relaxes blood vessels |
Constricts blood vessels |
|
Reduces water retention |
Increases water retention |
|
Lowers Blood Pressure |
Increases blood pressure |
|
PGE1 prevents Arachidonic Acid (AA) release |
Are products of Arachidonic Acid. |
|
|
|
The important thing
to recognize is that these collections are opposed in their function. It’s not
that we want to block Series 2. We want blood vessels to constrict at times to
maintain blood pressure, we want water balance, etc. It is, however, that we
want a BALANCE of these functions! This is the critical point. An over
expression of Series 2 prostaglandins leads to a great fraction of the chronic
problems seen by everyday folks, pain and inflammation in joints, headaches,
high blood pressure, allergies, etc. We find that a balance of these essential
fats can minimize, or often alleviate many if not all of these functions.
NOTE! Aspirin,
ibuprofen, acetaminophen, (NSAIDS) are broad spectrum prostaglandin blockers.
They stop pain and reduce inflammation by blocking ALL Series. This is bad,
because the Series 1 and 2 are needed to maintain proper function of organs.
That is why so many problems are associated with chronic use of these medicines.
(See NSAIDS)
As a result of the
need for more potent, less problematic medicines, other new drugs, some called
COX inhibitors are now being promoted. Note the following:

The COX pathway leads to series 2 prostaglandins, which are
problematic in excess. Blocking this pathway selectively blocks the production.
Note also, however, the LOX series. These lead to substances known as
Leukotrienes. These promote the aggregation of white blood cells, constrict
smooth muscle and are strongly involved in inflammatory diseases such as
asthma, arthritis, inflammatory bowel syndrome and much, much more. So, guess
what? There are (you guessed it) LOX inhibitors as well. It’s a cascading
nonsense.
It is the case that people, generally, are suffering from an
overproduction of Arachidonic Acid leading to the prostaglandins and
leukotrienes, pain, inflammation, etc.
Note from the metabolic fate chart above, that the production of
Arachidonic Acid follows the Linoleic Acid (LA) pathway and is inhibited by the
alpha-Linolenic Acid (ALA) pathway. Thus, it seems that we are getting too much
LA and not enough ALA. Do our dietary practices bear this out? Oh yes!
LA comes principally from vegetable oils such as corn oil and
others. We are SWIMMING in corn oil! It is a principle crop in this nation and
is the component of most table, cooking and production oils.
ALA comes from raw seeds and cold water fish. As a bonus, Fish
contains the other two fatty acids mentioned at the top of this page and
farther along the ALA right-side pathway, EPA and DHA. That’s why fish is so
highly beneficial.
AA comes preformed in animal fats. That’s why saturated animal fat
is pro-inflammatory.
Now think, how much of each do you consume daily? Further, ALA is
easily turned rancid by exposure to light and oxygen and rapidly oxidized by
excessive heat. The truth is, it is very difficult in today’s food environment
to get enough ALA. That’s why it’s so important to get good quality fresh cold
water fish and supplement with undamaged seed oil such as Flax Seed Oil.
Check these clinical studies…EFA Studies and these Abstracts from Studies in PDF format.
A VERY important thing to realize in the India Heart
Study is the inclusion of antioxidants, vitamins/minerals and fruits and
vegetables. These are critical to prevent oxidation of the fats in the body.
Oxidation processes are extremely important in disease and aging. See the
section on Antioxidants.